NAD+ is sold around Las Vegas two ways: as a drip that takes an hour and a half, and as a shot. The pages that compare them like to call the drip a deep reset and the shot steady upkeep. That isn't the real difference. At Las Vegas Mobile IV Therapy they're two separate products, priced and given differently, and neither is a stronger dose of the other. Both cost a few hundred dollars, so it pays to know which one you're actually buying.
- 1 The drip and the injection, side by side
- 2 What each costs, milligram for milligram
- 3 NAD+ drip side effects: what a real-world study found
- 4 What to expect during an NAD+ drip, start to finish
- 5 Is an NAD+ drip worth it?
- 6 Choosing between them
- 7 Is NAD+ just vitamin B12?
- 8 Other questions about NAD+ drips and injections
- 9 Sources
The drip and the injection, side by side
| NAD+ drip | NAD+ injection | |
|---|---|---|
| What it is | A 500 ml bag of normal saline with NAD+ and a B-complex, given by IV | A compounded NAD+ vial, given by injection |
| How it's given | A licensed nurse or REMT places the IV | First dose at a visit with a licensed professional; the rest at home |
| Time at the visit | 90-minute treatment, booked as a 135-minute slot | Booked as a 30-minute slot |
| Before it starts | You book online or by phone | An exam and a provider's approval of the prescription |
| What you leave with | Nothing | The vial, for the rest of its 500 mg |
| Price | $100 plus $1 per mg | $200 per 500 mg vial |
The drip is a visit. A licensed nurse or REMT comes to you and places the IV, and a 500 ml bag of normal saline with NAD+ and a B-complex runs in over 90 minutes. Nothing goes home with you. The price is set by how many milligrams of NAD+ are in the bag.
The injection is a prescription. The NAD+ is compounded for one person, and you need an exam and a provider's approval before anything is dispensed. Your first dose happens at a visit with a licensed professional, booked as a 30-minute slot. After that the vial stays with you, and you continue at home. It's a prescription you keep, not a shot at a clinic.
Your provider sets the vial's schedule. How often people take NAD+ injections is a separate question with its own guide.
What each costs, milligram for milligram
The drip is priced in two parts: a $100 base plus $1 for each milligram of NAD+. At 250 mg that comes to $350. At 500 mg it's $600, not $500. The base is part of every total, and a price table that leaves it out understates the bill by $100.
The vial is $200 for 500 mg.
Put side by side, a 100 mg drip costs the same as a 500 mg vial. At 500 mg, the drip works out to $1.20 a milligram and the vial to $0.40.
Two things change what a drip visit costs. Between 8:00 PM and 7:00 AM there's a $99 after-hours fee, so a 500 mg drip at midnight comes to $699. The $50 deposit you pay when you book is credited to that total, not added to it.
That arithmetic compares what you pay. It doesn't compare what you get. No outcome trial has measured that for either one, for wellness or ageing.
NAD+ drip side effects: what a real-world study found
An NAD+ drip can feel rough. The forum threads have that right. A 2026 study in Frontiers in Aging went back through a commercial IV clinic's charts. Six adults had 500 mg of NAD+ in 500 ml of saline on four days in a row, and each person set their own drip rate.
Every one of those stopped as soon as the infusion finished. Because people slowed their drips to cope, the infusions averaged 97 minutes, and the times varied widely.
Flushing is the other effect you'll read about. A 2026 review of IV NAD+, also in Frontiers in Aging, lists it with nausea, cramping and chest discomfort, and says anecdotal reports from wellness clinics tie that kind of discomfort to fast drips.
Read the study for what it is. It covers six people, it looks back at charts rather than testing anything, and its authors work for the research arm of the chain that gave the infusions. It still points one way: the symptoms are common, they come with the drip, and they end with it. If they start, tell your nurse or REMT right away rather than sitting through them.
What to expect during an NAD+ drip, start to finish
You book online or by phone, and a $50 deposit is taken when you book. We're open 24 hours. In the Las Vegas metro the usual wait from booking is 45 to 60 minutes, fastest on the Strip and Downtown and a little longer to Henderson and Summerlin. At peak times (weekend mornings, holidays, convention weeks) it can run to 90.
A licensed nurse or REMT arrives wherever you're staying, a home or a hotel room, working under the medical oversight of our Medical Director, Dr. Daniel Olivero, MD. They place the IV and hang a 500 ml bag of normal saline with NAD+ and a B-complex added.
The treatment is 90 minutes, and the appointment is booked as a 135-minute slot. In the 2026 chart study, drips that people slowed averaged 97 minutes and varied widely, so clear the whole slot and don't plan anything tight after it.
Is an NAD+ drip worth it?
If worth it means the drip will do more for your energy or your ageing than the injection would, nobody can tell you that. It hasn't been tested. A 2026 systematic review in Ageing Research Reviews went through 113 studies of NAD+ and the compounds the body turns into it, 33 of them in people, published from 2010 to October 2025. It found no outcome trial of NAD+ itself given into a vein or a muscle for wellness or ageing. The 2026 review of IV NAD+ in Frontiers in Aging called the evidence preliminary and not enough to support routine wellness use.
So when a comparison page says the drip works faster and the injection works more gently, neither claim has a study under it. Neither route has been shown to beat the other at anything you'd feel.
That leaves four things you can actually weigh. The time: 90 minutes or more for the drip, against a short visit and doses at home. The money: $1.20 a milligram for a 500 mg drip, $0.40 for the vial. Who holds the needle: a nurse or REMT, or you. And how you'd handle a drip that can feel rough.
Choosing between them
The drip fits if you want it done in one sitting by a nurse or REMT, you'd rather not handle injections yourself, and an hour and a half or more in a hotel room or on your own couch is fine. You can book an NAD+ drip at home on its page, which sets out the dose pricing.
The vial fits if you'd rather not sit through a drip, you're comfortable continuing at home once you've been shown how, and you're willing to start with an exam and a provider's approval. Because it's a prescription, it starts with a call to 725-217-4236 rather than a booking button.
If you're planning more than one drip, how often to do NAD+ covers spacing.
Is NAD+ just vitamin B12?
No. NAD+ is a coenzyme your cells build from vitamin B3 (niacin) and the amino acid tryptophan. Vitamin B12, also called cobalamin, is a different vitamin altogether: it helps form red blood cells and keeps the nervous system working.
The mix-up is easy to make. Both are sold as injections, and ours sit on the same menu. Our NAD+ drip also carries a B-complex. But our menu lists B-complex and B12 as separate ingredients. The Hydration and the Myers' Cocktail IV carry both. The NAD+ bag lists the B-complex and no B12.
Other questions about NAD+ drips and injections
Sources
- Reyna K, Heinzen G, Patel N, Ritter M, Siojo A, Legere H, Pojednic R. Intravenous infusion of nicotinamide adenine dinucleotide (NAD+) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting. Frontiers in Aging, 2026.
- Gallagher C, Emmanuel OO. NAD+ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence. Ageing Research Reviews, 2026.
- Alangari A, Arif J, Al Qureshah F, Alkhodairy F. Narrative review of intravenous NAD+ and NAD+ precursors in wellness and translational medicine. Frontiers in Aging, 2026.
- MedlinePlus Medical Encyclopedia. Niacin.
- MedlinePlus Medical Encyclopedia. Vitamin B12.
- Migaud ME, Ziegler M, Baur JA. Regulation of and challenges in targeting NAD+ metabolism. Nature Reviews Molecular Cell Biology, 2024.
- Nevada State Board of Nursing. Practice Decision: RN Scope in Out of Hospital Administration of IV Solutions and Medications. Approved by the Board November 18, 2020.
